BRAF V600E mutations are characteristic for papillary craniopharyngioma and may coexist with CTNNB1-mutated adamantinomatous craniopharyngioma

Acta Neuropathol. 2014;127(6):927-9. doi: 10.1007/s00401-014-1270-6. Epub 2014 Apr 9.

Authors

Sarah Jane Larkin¹, Veronica Preda, Niki Karavitaki, Ashley Grossman, Olaf Ansorge

Affiliation

¹ Nuffield Department of Clinical Neurosciences, Department of Neuropathology, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK.

No abstract available

Publication types

Letter

MeSH terms

Craniopharyngioma / genetics*
Craniopharyngioma / metabolism
Craniopharyngioma / pathology
Genetic Predisposition to Disease
Humans
Immunohistochemistry
Mutation*
Pituitary Neoplasms / genetics*
Pituitary Neoplasms / metabolism
Pituitary Neoplasms / pathology
Proto-Oncogene Proteins B-raf / genetics*
Proto-Oncogene Proteins B-raf / metabolism
beta Catenin / genetics*
beta Catenin / metabolism

Substances

CTNNB1 protein, human
beta Catenin
BRAF protein, human
Proto-Oncogene Proteins B-raf