Aortic root rupture after TAVR in two renal transplant patients on chronic immunosuppressant therapy

Catheter Cardiovasc Interv. 2015 Apr;85(5):909-15. doi: 10.1002/ccd.25513. Epub 2014 Nov 4.

Abstract

Patients on chronic immunosuppressant therapy after renal transplantation have a high rate of in-hospital mortality and approximately 20% mortality rate per year after conventional valve surgery. While transcatheter aortic valve replacement (TAVR) is an appealing option to consider for such patients, there are not significant outcome data for the procedure in this patient population. We report two cases of aortic root rupture after TAVR in renal transplant patients on chronic immunosuppressant therapy.

Keywords: TAVR; aortic rupture; renal transplant.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Aorta, Thoracic
  • Aortic Rupture / diagnosis
  • Aortic Rupture / etiology*
  • Aortic Valve Stenosis / complications
  • Aortic Valve Stenosis / surgery*
  • Echocardiography, Transesophageal
  • Fatal Outcome
  • Female
  • Graft Rejection / complications
  • Graft Rejection / drug therapy*
  • Humans
  • Immunosuppressive Agents / therapeutic use*
  • Kidney Failure, Chronic / surgery
  • Kidney Transplantation*
  • Middle Aged
  • Multidetector Computed Tomography
  • Transcatheter Aortic Valve Replacement / adverse effects*

Substances

  • Immunosuppressive Agents