Cortical microinfarcts on 7T MRI in patients with spontaneous intracerebral hemorrhage

J Cereb Blood Flow Metab. 2014 Jul;34(7):1104-6. doi: 10.1038/jcbfm.2014.73. Epub 2014 Apr 23.

Abstract

In patients with spontaneous intracerebral hemorrhage (ICH) coexisting abnormalities on brain imaging can provide clues on the etiology of the underlying small vessel disease. We examined cortical cerebral microinfarcts as a novel marker of coexistent vascular damage in ICH. Twelve patients with spontaneous ICH and 15 controls underwent 7Tesla magnetic resonance imaging (MRI). Microinfarcts were present in 9 of 12 patients with spontaneous ICH, and in 5 of 15 controls. This explorative study shows, for the first time, that microinfarcts appear to be a very common vascular comorbidity in spontaneous ICH. Future larger studies should further assess the etiological significance of these lesions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Cerebral Hemorrhage / complications*
  • Cerebral Hemorrhage / pathology*
  • Cerebral Infarction / complications*
  • Cerebral Infarction / pathology*
  • Female
  • Humans
  • Magnetic Resonance Imaging / methods
  • Male
  • Middle Aged