Reconstructing complex tissues from single-cell analyses

Lu Wen; Fuchou Tang

doi:10.1016/j.cell.2014.04.024

Reconstructing complex tissues from single-cell analyses

Cell. 2014 May 8;157(4):771-3. doi: 10.1016/j.cell.2014.04.024.

Authors

Lu Wen¹, Fuchou Tang²

Affiliations

¹ Biodynamic Optical Imaging Center, College of Life Sciences, Peking University, Beijing 100871, China.
² Biodynamic Optical Imaging Center, College of Life Sciences, Peking University, Beijing 100871, China. Electronic address: tangfuchou@pku.edu.cn.

PMID: 24813603
DOI: 10.1016/j.cell.2014.04.024

Abstract

Techniques for profiling individual cells are rapidly advancing and are providing an unprecedented opportunity for studying the genetic regulation of development and disease. In this issue, Durruthy-Durruthy et al. analyze gene expression at the single-cell level for a simple but highly organized three-dimensional structure, the mouse otocyst.

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MeSH terms

Animals
Ear, Inner / cytology*
Ear, Inner / embryology*
Female
Male
Neural Stem Cells / cytology*
Single-Cell Analysis*
Transcriptome*