Genetic heterogeneity of bovine noroviruses in Italy

Arch Virol. 2014 Oct;159(10):2717-22. doi: 10.1007/s00705-014-2109-0. Epub 2014 May 14.

Abstract

By screening 104 faecal samples from asymptomatic calves in Italy, bovine norovirus RNA was detected with a prevalence rate of 10.5 % (11/104). A continuous sequence spanning the RdRp region and the 5' end of the capsid gene was generated for 7 of the 11 strains. Upon phylogenetic analysis, five strains were grouped with GIII.2 Newbury2-like viruses, and one strain was grouped with GIII.1 Jena-like noroviruses. Interestingly, one strain (80TE/IT) was genetically related to the GIII.1/Jena/80/De in the RdRp but resembled the GIII.2/Newbury2/76/UK in the capsid gene, suggesting a recombination event occurring in the ORF1/ORF2 junction region.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Caliciviridae Infections / epidemiology
  • Capsid Proteins / genetics*
  • Cattle
  • Cattle Diseases / epidemiology
  • Feces / virology
  • Genetic Heterogeneity*
  • Genetic Variation
  • Italy / epidemiology
  • Molecular Sequence Data
  • Norovirus / classification*
  • Norovirus / genetics*
  • Norovirus / isolation & purification
  • Open Reading Frames / genetics*
  • Recombination, Genetic
  • Viral Structural Proteins / genetics

Substances

  • Capsid Proteins
  • Viral Structural Proteins

Associated data

  • GENBANK/KC896779
  • GENBANK/KC896780
  • GENBANK/KC896781
  • GENBANK/KC896782
  • GENBANK/KC896783
  • GENBANK/KC896784
  • GENBANK/KC896785
  • GENBANK/KC896786
  • GENBANK/KC896787
  • GENBANK/KC896788
  • GENBANK/KC896789