Many fences make better neighbors

Franz J Zemp; Christopher C M Waterhouse; Paul Kubes

doi:10.1126/scitranslmed.3009391

Many fences make better neighbors

Sci Transl Med. 2014 May 21;6(237):237fs22. doi: 10.1126/scitranslmed.3009391.

Authors

Franz J Zemp¹, Christopher C M Waterhouse², Paul Kubes¹

Affiliations

¹ Department of Physiology and Pharmacology, Snyder Institute of Chronic Disease, University of Calgary, T2N 4N1, Canada. fjzemp@ucalgary.ca pkubes@ucalgary.ca.
² Department of Pediatrics, Alberta Children's Hospital Research Institute, University of Calgary, T2N 4N1, Canada.

PMID: 24848254
DOI: 10.1126/scitranslmed.3009391

Abstract

Phagocytic Kupffer cells in the liver act as a firewall that captures commensal bacteria that have breached the barrier of the gut mucosa (Balmer et al., this issue).

Publication types

Comment

MeSH terms

Animals
Bacterial Translocation*
Female
Host-Pathogen Interactions*
Humans
Intestines / blood supply*
Intestines / microbiology*
Liver / blood supply*
Liver / microbiology*
Liver Circulation*
Liver Diseases / microbiology*
Male