Whole-lung irradiation in the treatment of metastatic synovial sarcoma

Pediatr Blood Cancer. 2014 Nov;61(11):2092-3. doi: 10.1002/pbc.25114. Epub 2014 Jun 17.

Abstract

Whole-lung irradiation (WLI) is standard of care in the treatment of patients with rhabdomyosarcoma, Ewing sarcoma, and Wilms tumor and pulmonary metastases. However, it is not routinely utilized in the treatment of pulmonary metastases arising from other soft tissue sarcoma histologies. A patient presented with synovial sarcoma of his groin and punctate pulmonary metastases. After completion of multimodality treatment to his primary lesion, he received WLI. The patient is without evidence of disease at 3.8 years. This case demonstrates the need for further study of WLI in synovial sarcoma as it may improve outcomes in patients with this disease.

Keywords: distant metastases; soft tissue sarcoma; whole-lung irradiation.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Humans
  • Lung / radiation effects
  • Lung Neoplasms / radiotherapy*
  • Lung Neoplasms / secondary*
  • Male
  • Sarcoma, Synovial / pathology
  • Sarcoma, Synovial / secondary*
  • Tomography, X-Ray Computed