Imatinib non-responsive chronic eosinophilic leukemia with ETV6-PDGFRA fusion gene

Leuk Lymphoma. 2015 Mar;56(3):768-9. doi: 10.3109/10428194.2014.938330. Epub 2014 Aug 18.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Chromosomes, Human, Pair 12 / genetics
  • Chromosomes, Human, Pair 4 / genetics
  • Drug Resistance, Neoplasm / genetics
  • ETS Translocation Variant 6 Protein
  • Humans
  • Hypereosinophilic Syndrome / drug therapy*
  • Hypereosinophilic Syndrome / genetics*
  • Imatinib Mesylate / therapeutic use*
  • In Situ Hybridization, Fluorescence
  • Karyotype
  • Leukemia
  • Male
  • Middle Aged
  • Oncogene Proteins, Fusion / genetics*
  • Proto-Oncogene Proteins c-ets / genetics*
  • Receptor, Platelet-Derived Growth Factor alpha / genetics*
  • Repressor Proteins / genetics*
  • Translocation, Genetic

Substances

  • Antineoplastic Agents
  • Oncogene Proteins, Fusion
  • Proto-Oncogene Proteins c-ets
  • Repressor Proteins
  • Imatinib Mesylate
  • Receptor, Platelet-Derived Growth Factor alpha

Supplementary concepts

  • Pdgfra-Associated Chronic Eosinophilic Leukemia