Velocities of weight, height and fat mass gain during potentially critical periods of growth are decisive for adult body composition

Eur J Clin Nutr. 2015 Feb;69(2):262-8. doi: 10.1038/ejcn.2014.131. Epub 2014 Jul 9.

Abstract

Objectives: To examine whether maximal velocities of weight, height and fat mass during potentially critical periods of growth were associated with body composition in young adulthood.

Subjects/methods: Analyses were performed on 277 female and 271 male participants of the DOrtmund Nutritional and Anthropometric Longitudinally Designed (DONALD) study with anthropometric measurements in young adulthood (18-25 years) as well as early life (0-2 years), mid-childhood (3-8 years) or puberty (9-15 years). Maximum growth velocities were calculated using the SuperImposition by Translation And Rotation (SITAR) routine or polynomial functions and related to adult fat mass index (FMI) and fat-free mass index (FFMI).

Results: In early life, faster weight gain was associated with a moderately higher FMI and FFMI in young adulthood in women only (Ptrend=0.01). In mid-childhood and puberty, weight and fat mass velocities were related to adult FMI and FFMI in both sexes (Ptrend⩽0.002): relative differences between the highest and lowest tertiles of these growth velocities ranged 33-69% for adult FMI and 6-12% for adult FFMI. A higher mid-childhood height velocity was related to a modestly higher adult FMI in women only (Ptrend=0.0005).

Conclusions: Faster gain in weight and body fat during mid-childhood and puberty appear to be particularly relevant for adult fat mass.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue / metabolism*
  • Adolescent
  • Adult
  • Anthropometry
  • Body Composition*
  • Body Fluid Compartments / metabolism
  • Body Height*
  • Body Mass Index
  • Body Weight
  • Child
  • Child, Preschool
  • Female
  • Growth / physiology*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Obesity / etiology*
  • Obesity / metabolism
  • Puberty
  • Sex Factors
  • Sexual Maturation
  • Weight Gain*
  • Young Adult