[Methemoglobinemia after accidental Nestosyl ingestion]

Arch Fr Pediatr. 1989 Apr;46(4):271-2.
[Article in French]

Abstract

Nestosyl is usually used for dental pain in children. We report a methemoglobinemia after accidental ingestion of 10 ml in a 2 year-old girl. Cyanosis was cleared and O2 saturation and PaO2 were normalized 15 mn after methylene blue (1 mg/kg) administered intravenously. Nestosyl contains butoform, benzocaine, resorcine and 8-hydroxyquinoleine: the 3 latest can induce methemoglobinemia. The benefit of the drug is not demonstrated and this potentially severe side effect justifies its delivery only after medical prescription and information about its dangers.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Anesthetics, Local / poisoning*
  • Cyanosis / etiology
  • Drug Combinations / poisoning
  • Female
  • Humans
  • Hydroxyquinolines / poisoning*
  • Infant
  • Methemoglobinemia / chemically induced*
  • Methemoglobinemia / complications
  • Oxyquinoline / poisoning*

Substances

  • Anesthetics, Local
  • Drug Combinations
  • Hydroxyquinolines
  • Oxyquinoline
  • Nestosyl ointment