Abstract
Host defence peptidotoxins from animal venoms have been identified to possess substantial anticancer properties. Towards a safer, translatable approach, we have developed a viable chemical methodology based on a well-defined, self-assembled polymeric nano-architecture for controlled delivery of toxins derived from scorpion venom.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / pharmacology*
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Cell Line, Tumor
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Dose-Response Relationship, Drug
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Drug Screening Assays, Antitumor
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Humans
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MCF-7 Cells
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Models, Molecular
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Molecular Structure
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Nanostructures / chemistry*
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Particle Size
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Scorpion Venoms / chemistry*
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Scorpion Venoms / pharmacology*
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Structure-Activity Relationship
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Surface Properties
Substances
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Antineoplastic Agents
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Scorpion Venoms