Neurosharing: large-scale data sets (spike, LFP) recorded from the hippocampal-entorhinal system in behaving rats

Kenji Mizuseki; Kamran Diba; Eva Pastalkova; Jeff Teeters; Anton Sirota; György Buzsáki

doi:10.12688/f1000research.3895.1

Neurosharing: large-scale data sets (spike, LFP) recorded from the hippocampal-entorhinal system in behaving rats

F1000Res. 2014 Apr 30:3:98. doi: 10.12688/f1000research.3895.1. eCollection 2014.

Authors

Kenji Mizuseki¹, Kamran Diba², Eva Pastalkova³, Jeff Teeters⁴, Anton Sirota⁵, György Buzsáki⁶

Affiliations

¹ NYU Neuroscience Institute, Langone Medical Center, New York University, New York, NY, USA ; Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ, USA ; Allen Institute for Brain Science, Seattle, WA, USA.
² Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ, USA ; Department of Psychology, University of Wisconsin at Milwaukee, Milwaukee, WI, USA.
³ Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ, USA ; Janelia Farm Research Campus, Howard Hughes Medical Institute, Ashburn, VA, USA.
⁴ Redwood Center for Theoretical Neuroscience, University of California, Berkeley, Berkeley, CA, USA.
⁵ Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ, USA ; Centre for Integrative Neuroscience, University of Tübingen, Tübingen, Germany.
⁶ NYU Neuroscience Institute, Langone Medical Center, New York University, New York, NY, USA ; Center for Molecular and Behavioral Neuroscience, Rutgers, The State University of New Jersey, Newark, NJ, USA ; Center for Neural Science, New York University, New York, NY, USA.

Abstract

Using silicon-based recording electrodes, we recorded neuronal activity of the dorsal hippocampus and dorsomedial entorhinal cortex from behaving rats. The entorhinal neurons were classified as principal neurons and interneurons based on monosynaptic interactions and wave-shapes. The hippocampal neurons were classified as principal neurons and interneurons based on monosynaptic interactions, wave-shapes and burstiness. The data set contains recordings from 7,736 neurons (6,100 classified as principal neurons, 1,132 as interneurons, and 504 cells that did not clearly fit into either category) obtained during 442 recording sessions from 11 rats (a total of 204.5 hours) while they were engaged in one of eight different behaviours/tasks. Both original and processed data (time stamp of spikes, spike waveforms, result of spike sorting and local field potential) are included, along with metadata of behavioural markers. Community-driven data sharing may offer cross-validation of findings, refinement of interpretations and facilitate discoveries.

Abstract

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