Chromatin biochemistry enters the next generation of code 'seq-ing'

Erin K Shanle; Scott B Rothbart; Brian D Strahl

doi:10.1038/nmeth.3044

Chromatin biochemistry enters the next generation of code 'seq-ing'

Nat Methods. 2014 Aug;11(8):799-800. doi: 10.1038/nmeth.3044.

Authors

Erin K Shanle¹, Scott B Rothbart², Brian D Strahl²

Affiliations

¹ Department of Biochemistry &Biophysics, University of North Carolina at Chapel Hill, North Carolina, USA.
² 1] Department of Biochemistry &Biophysics, University of North Carolina at Chapel Hill, North Carolina, USA [2] Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, North Carolina, USA.

Abstract

Barcoded semisynthetic nucleosomes combined with massively parallel sequencing provide an innovative new platform for analyzing the histone-recognition and histone-modifying activities of chromatin-associated proteins.

Publication types

Comment

MeSH terms

Chromatin / chemistry*
DNA Barcoding, Taxonomic*

Substances

Chromatin

Abstract

Publication types

MeSH terms

Substances

Grants and funding