[Chronic thromboembolic pulmonary hypertension--a position paper]

Dtsch Med Wochenschr. 2014 Dec:139 Suppl 4:S155-65. doi: 10.1055/s-0034-1370220. Epub 2014 Aug 1.
[Article in German]

Abstract

This position paper summarises current developments in chronic thromboembolic pulmonary hypertension (CTEPH) including diagnostic approaches and treatment options. Based on the guidelines of the task force of CTEPH experts at the 5th World Symposium on Pulmonary Hypertension in Nice 2013. Open questions arising during the treatment of patients with CTEPH are addressed. Patients with suspected CTEPH should undergo echocardiography and cardiopulmonary exercise testing. A ventilation/perfusion scan is the recommended imaging test for screening in the diagnostic algorithm for the evaluation of CTEPH. CTEPH-patients should be discussed in an expert center with an interdisciplinary team and an experienced PEA surgeon to decide the further treatment. Pulmonary endarterectomy (PEA) is the treatment of choice for patients with CTEPH. Medical therapy with PH-targeted medications for inoperable CTEPH and residual disease after PEA should only be initiated if evaluation reveals that the patient is no candidate for a PEA. Current data suggest that CTEPH patients treated with PEA have a better long-term survival rate and quality of life than patients treated with medical therapy.

Publication types

  • Consensus Development Conference
  • English Abstract
  • Review

MeSH terms

  • Algorithms
  • Chronic Disease
  • Combined Modality Therapy
  • Cooperative Behavior
  • Echocardiography
  • Endarterectomy
  • Exercise Test
  • Humans
  • Hypertension, Pulmonary / diagnosis*
  • Hypertension, Pulmonary / mortality
  • Hypertension, Pulmonary / physiopathology
  • Hypertension, Pulmonary / therapy*
  • Interdisciplinary Communication
  • Mass Screening
  • Molecular Targeted Therapy
  • Practice Guidelines as Topic
  • Prognosis
  • Pulmonary Artery
  • Pulmonary Embolism / diagnosis*
  • Pulmonary Embolism / mortality
  • Pulmonary Embolism / physiopathology
  • Pulmonary Embolism / therapy*
  • Survival Rate
  • Tertiary Care Centers
  • Ventilation-Perfusion Ratio / physiology