Sexual abuse is a traumatic event with heavy consequences in terms of clinical implications and quality or quantity of life. The mediation of the development of post-traumatic stress disorder accounts for many of the presented symptoms, but not for the whole range of them, especially if violence is suffered during childhood. From the analysis of its epidemiology and consequences, it can be derived that this disorder is dramatically widespread and cannot be any longer ignored but preventive efforts and early intervention are required. Current therapeutic options that have been proven to be effective are discussed, though further research is warranted to improve treatment strategies.