Health-related quality of life in pediatric intestinal transplantation

Pediatr Transplant. 2014 Nov;18(7):746-56. doi: 10.1111/petr.12348. Epub 2014 Sep 2.

Abstract

To determine HRQOL after pediatric intestinal transplantation. Thirty-four IT survivors from 1999 to 2012 were asked to complete age-specific HRQOL non-disease-specific questionnaires: TAPQOL (0-4 yr), KINDL-R (5-7 yr; 8-12 yr; 13-17 yr), and SF-36v2 (>18 yr), all validated with Spanish population. Primary caregiver completed a SF-36 questionnaire and CBI. Thirty-one participants were included. Median age was 10.2 yr (1-29) and time after transplant 4.4 yr (0-13). Overall patient scores were 78.2 ± 10.6 (n = 8), 83.3 ± 9.7 (n = 6), 72.2 ± 9.21 (n = 6), 80.5 ± 12.4 (n = 7), and 82.2 ± 12.4 (n = 4) for each age group. Highest scores were obtained for vitality (group I), self-esteem (group IV), and physical and social functioning and emotions (group V). Lowest scores were obtained in appetite and behavior (I), family and school (III), and chronic disease perception (III, IV). No significant differences were found between caregivers and their children. CBI showed stress in 52%. SF-36 for caregivers was lower than general population. No significant differences were found depending on relevant clinical and sociodemographic data. HRQOL was acceptable and improved with age and time since transplantation. Parents had a slighter own QOL and worse perception of health than their children. When successful, intestinal transplantation allows a normal life in most patients and can be offered as an attractive option.

Keywords: children; health-related quality of life; intestinal transplantation.

MeSH terms

  • Adolescent
  • Adult
  • Caregivers
  • Child
  • Child, Preschool
  • Female
  • Health Status
  • Humans
  • Infant
  • Intestines / transplantation*
  • Male
  • Quality of Life*
  • Regression Analysis
  • Spain
  • Surveys and Questionnaires
  • Transplantation / psychology*
  • Young Adult