1 aUniversity of Padova, Padua bUniversity of Perugia, Perugia, Italy cUniversity of Western Australia, Perth, Australia dJichi University, Tochigi eTohoku University, Sendai fShiga University of Medical Science, Otsu, Japan gUniversity of Chieti, Chieti, Italy hColumbia University iStony Brook University, New York, USA jFlinders University, Adelaide, Australia kHospital of Assisi, Italy.