[Macrophage activation and Mycobacterium leprae: effect of interferon gamma on the production of oxygen free radicals by phagocytic cells]

Abstract

Activation of the respiratory metabolic channel (F.O.R.), responsible in part for the bactericidal effect, was measured in vitro by a chemoluminescence test on circulating phagocytes. All mycobacteria tested, except for Mycobacterium leprae, induced a significant response. Its effect on lepromatous leprosy pathology is a subject for discussion.