Effect of bioprocessing of wheat bran in wholemeal wheat breads on the colonic SCFA production in vitro and postprandial plasma concentrations in men

Nuria Mateo Anson; Robert Havenaar; Wouter Vaes; Leon Coulier; Koen Venema; Emilia Selinheimo; Aalt Bast; Guido R M M Haenen

doi:10.1016/j.foodchem.2011.03.043

Effect of bioprocessing of wheat bran in wholemeal wheat breads on the colonic SCFA production in vitro and postprandial plasma concentrations in men

Food Chem. 2011 Sep 15;128(2):404-9. doi: 10.1016/j.foodchem.2011.03.043. Epub 2011 Mar 21.

Authors

Nuria Mateo Anson¹, Robert Havenaar², Wouter Vaes², Leon Coulier², Koen Venema², Emilia Selinheimo³, Aalt Bast⁴, Guido R M M Haenen⁴

Affiliations

¹ TNO Quality of Life, P.O. Box 360, 3700 AJ Zeist, The Netherlands; University of Maastricht, P.O. Box 616, 6200 MD Maastricht, The Netherlands. Electronic address: nuria.mateoanson@maastrichtuniversity.nl.
² TNO Quality of Life, P.O. Box 360, 3700 AJ Zeist, The Netherlands.
³ VTT, Technical Research Centre of Finland, Espoo, FI-02044 VTT, Finland.
⁴ University of Maastricht, P.O. Box 616, 6200 MD Maastricht, The Netherlands.

PMID: 25212148
DOI: 10.1016/j.foodchem.2011.03.043

Abstract

The health benefits of whole grain consumption can be partly attributed to the inclusion of the bran or outer-layers of the grain rich in dietary fibre. Fibre is fermented in the colon, leading to the production of beneficial metabolites, such as short-chain fatty acids (SCFA). The effect of five different types of bread on the SCFA production was studied in an in vitro model of human colon. Additionally, the postprandial effects of two selected breads on the SCFA plasma concentrations were investigated in men. A higher in vitro production of butyrate was induced by wholemeal wheat bread with bioprocessed bran than by native bran. The increase in butyrate seemed to be in exchange for propionate, whilst the total SCFA production remained similar. However, differences between the two breads in the postprandial butyrate concentrations could not be detected in peripheral blood of men, probably due to an effective utilisation by colonocytes.

Keywords: Bioprocessing; Butyrate; Fibre; Wheat bran.