Neuromuscular complications of critical illness

Crit Care Clin. 2014 Oct;30(4):785-94. doi: 10.1016/j.ccc.2014.06.008. Epub 2014 Jul 30.

Abstract

Neuromuscular sequelae are common in the critically ill. Critical illness polyneuropathy and critical illness myopathy are neuromuscular complications of sepsis or iatrogenic complications of treatments required in intensive care. This article discusses the diagnosis, treatment, and prognosis of these disorders based on a literature review. This review found that glycemic control, early mobilization, and judicious use of steroids and neuromuscular blocking agents are the primary approaches to reduce the incidence and severity of neuromuscular complications in affected patients.

Keywords: Acute quadriplegic myopathy; Critical illness myopathy; Critical illness polyneuropathy; Neuromuscular disorders; Sepsis.

Publication types

  • Review

MeSH terms

  • Critical Care / methods*
  • Critical Illness / therapy*
  • Humans
  • Muscular Diseases / diagnosis
  • Muscular Diseases / etiology*
  • Muscular Diseases / therapy*
  • Polyneuropathies / diagnosis
  • Polyneuropathies / etiology*
  • Polyneuropathies / therapy*
  • Practice Guidelines as Topic
  • Prognosis
  • Sepsis / complications*