Effective chemical constituent's identification of extracting solution from herbs - a review

Afr J Tradit Complement Altern Med. 2014 Apr 3;11(3):53-69. doi: 10.4314/ajtcam.v11i3.9. eCollection 2014.

Abstract

Background and objective: The aim of this article, was the definition, and targets of possible mechanisms of Yin lai Decoction by retrieving the herbals in the decoction and integrating information from multi-databases, which can be guidance for the followed experimental study.

Matherials and methods: The information from multi-databases was integrated.

Results: In the study, we discovered 92 possible gene targets of Yin lai Decoction, 87% of which appeared in the targets of Flos Lonicerae, Fructus Forsythiae and Scutellaria baicalensis Georgi. The function of these targets focuses on the anti-infection and regulating immune system, and metabolism of the body.

Conclusion: Yin lai Decoction may affect the process of metabolism, immune response and infection by impact on the 92 possible gene targets, then it can mitigate the damage caused by infection and promote the body to health. But the definite mechanisms must be explored by further experimental study.

Keywords: Gene targets; Immune response; Infection; Metabolism; Yin lai Decoction.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Databases, Factual
  • Drugs, Chinese Herbal / chemistry
  • Drugs, Chinese Herbal / pharmacology*
  • Gene Expression Regulation / drug effects
  • Humans
  • Immune System / drug effects
  • Metabolism / drug effects
  • Plants, Medicinal / chemistry*

Substances

  • Drugs, Chinese Herbal