Improved prognosis following renin-angiotensin-aldosterone system blockade in patients undergoing concomitant aortic and mitral valve replacement

Int J Cardiol. 2014 Dec 15;177(2):680-2. doi: 10.1016/j.ijcard.2014.09.163. Epub 2014 Oct 5.

Authors

Kai-Hang Yiu¹, Wing-Shun Ng², Daniel Chan³, Ko-Yung Sit³, Arthur Wong⁴, Chun-Wai Lee², Hoi-Leong Chum², Wai-Yeung Cheng², Chung-Ting Pun², Kar-Lai Ho³, Yan Chen⁴, Lai-Ming Ho⁵, Cyrus Rustam Kumana⁶, Hung-Leong Cheung², Ma-Chan Chung², Chu-Pak Lau⁴, Wing-Kok Au³, Hung-Fat Tse⁷

Affiliations

¹ Division of Cardiology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China; Research Centre of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China. Electronic address: khkyiu@hku.hk.
² Department of Surgery, Queen Elizabeth Hospital, Hong Kong, China.
³ Department of Surgery, University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
⁴ Division of Cardiology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
⁵ School of Public Health, University of Hong Kong, Hong Kong, China.
⁶ Division of Clinical Pharmacology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China.
⁷ Division of Cardiology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China; Research Centre of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong, China. Electronic address: hftse@hku.hk.

PMID: 25449483
DOI: 10.1016/j.ijcard.2014.09.163

No abstract available

Keywords: ACEI; ARB; DVR; Prognosis; Renin–angiotensin–aldosterone system.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Aldosterone / metabolism
Angiotensin Receptor Antagonists / pharmacology
Angiotensin Receptor Antagonists / therapeutic use*
Angiotensin-Converting Enzyme Inhibitors / pharmacology
Angiotensin-Converting Enzyme Inhibitors / therapeutic use*
Aortic Valve
Bicuspid Aortic Valve Disease
Female
Follow-Up Studies
Heart Defects, Congenital / diagnosis*
Heart Defects, Congenital / mortality
Heart Defects, Congenital / therapy
Heart Valve Diseases / diagnosis*
Heart Valve Diseases / mortality
Heart Valve Diseases / therapy
Heart Valve Prosthesis Implantation / mortality
Heart Valve Prosthesis Implantation / trends*
Humans
Male
Middle Aged
Mitral Valve Insufficiency / diagnosis*
Mitral Valve Insufficiency / mortality
Mitral Valve Insufficiency / therapy
Mitral Valve Stenosis / diagnosis*
Mitral Valve Stenosis / mortality
Mitral Valve Stenosis / therapy
Prognosis
Renin-Angiotensin System / drug effects
Renin-Angiotensin System / physiology
Survival Rate / trends

Substances

Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors
Aldosterone