The IL-15 cytokine system provides growth and survival signals in Hodgkin lymphoma and enhances the inflammatory phenotype of HRS cells

Leukemia. 2015 May;29(5):1213-8. doi: 10.1038/leu.2014.345. Epub 2014 Dec 9.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Cell Proliferation
  • Gene Expression Regulation, Neoplastic*
  • Hodgkin Disease / metabolism*
  • Hodgkin Disease / mortality
  • Humans
  • Inflammation
  • Interleukin-15 / metabolism*
  • Killer Cells, Natural / cytology
  • MAP Kinase Signaling System
  • Phenotype
  • Receptors, Interleukin-15 / metabolism
  • Reed-Sternberg Cells / metabolism*
  • Signal Transduction
  • Treatment Outcome

Substances

  • IL15 protein, human
  • Interleukin-15
  • Receptors, Interleukin-15