[The continuum of COPD and cardiovascular risk: A global scenario of disease]

Clin Investig Arterioscler. 2015 May-Jun;27(3):144-7. doi: 10.1016/j.arteri.2014.09.003. Epub 2014 Dec 10.
[Article in Spanish]

Abstract

Chronic obstructive pulmonary disease (COPD) is a serious public health problem in our country. COPD is a treatable and preventable disease which is underdiagnosed. The EPISCAN study revealed a prevalence of 10.2% in Spain between individuals of 40-80 years, with 73% underdiagnosis. In Primary Care occupies 8.5% of all queries with a high economic impact. These patients exhibit some degree of systemic inflammation characterized by increased plasma levels of some inflammatory mediators such as IL-1, IL-6, IL-8, CRP and TNF, which are also related to endothelial disorders and arteriosclerosis. In the continuum of COPD, comorbidities most frequently appear are: ischemic heart disease, heart failure, stroke, hypertension, type 2 diabetes mellitus, renal failure, osteoporosis, myopathy, anxiety, depression, cognitive impairment, malnutrition, anemia and lung cancer.

Keywords: Agudización; COPD; Cardiovascular; Continuo; Continuous; Enfermedad pulmonar obstructiva crónica; Peaking.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cardiovascular Diseases / epidemiology*
  • Cardiovascular Diseases / physiopathology
  • Humans
  • Inflammation / epidemiology*
  • Inflammation / physiopathology
  • Inflammation Mediators / blood
  • Middle Aged
  • Prevalence
  • Pulmonary Disease, Chronic Obstructive / epidemiology
  • Pulmonary Disease, Chronic Obstructive / physiopathology*
  • Risk Factors
  • Spain / epidemiology

Substances

  • Inflammation Mediators