Biological properties of ligand-dependent activation of the MET receptor kinase in acute myeloid leukemia

Leukemia. 2015 May;29(5):1218-21. doi: 10.1038/leu.2014.348. Epub 2014 Dec 26.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Antineoplastic Agents / pharmacology
  • Binding, Competitive
  • Crizotinib
  • Gene Expression Regulation, Leukemic*
  • Humans
  • Leukemia, Myeloid, Acute / genetics*
  • Leukemia, Myeloid, Acute / metabolism*
  • Ligands
  • Models, Theoretical
  • Mutation
  • Phosphorylation
  • Protein Array Analysis
  • Protein Binding
  • Proto-Oncogene Proteins c-met / metabolism*
  • Pyrazoles / pharmacology
  • Pyridines / pharmacology
  • Signal Transduction
  • Thermodynamics

Substances

  • Antineoplastic Agents
  • Ligands
  • Pyrazoles
  • Pyridines
  • Crizotinib
  • MET protein, human
  • Proto-Oncogene Proteins c-met