Why the development of effective typhoid control measures requires the use of human challenge studies

Front Microbiol. 2014 Dec 16:5:707. doi: 10.3389/fmicb.2014.00707. eCollection 2014.

Authors

Claire Jones¹, Thomas C Darton¹, Andrew J Pollard¹

Affiliation

¹ Oxford Vaccine Group, Department of Paediatrics, National Institute for Health Research Oxford Biomedical Research Centre, University of Oxford Oxford, UK.

No abstract available

Keywords: Salmonella Typhi; diagnostics; enteric fever; host-pathogen interactions; human challenge studies; typhoid; typhoid vaccine.

Grants and funding

092661/Wellcome Trust/United Kingdom