Streptococcus bovis endocarditis: analysis of cases between 2005 and 2014

Braz J Infect Dis. 2015 Mar-Apr;19(2):209-12. doi: 10.1016/j.bjid.2014.12.007. Epub 2015 Jan 27.

Abstract

Background: Streptococcus bovis is a classical etiology of endocarditis and is associated with colonic lesions. No series of cases from Brazil has been described.

Objectives: To describe aspects of S. bovis endocarditis.

Methods: This is a case series of patients admitted to a cardiac surgery referral center, during the years 2005-2014. Clinical, laboratory, echochardiographic, colonoscopic, treatment, surgical and outcome variables were studied.

Results: Nine patients with S. bovis endocarditis were included; all cases fulfilled the modified Duke criteria. Incidence was 8/220 (4%) in years 2006-2014. There were seven male and two female patients; mean age was 56.7 years, standard deviation 13.4. All patients had native aortic valve involvement. Presentation was subacute in 7/9 (71%). Fever was present in 7/9 (77.7%), embolic lesions to solid organs occurred in three, and perivalvular abscess in two patients. All echocardiograms showed moderate to severe valvular regurgitation and vegetations. Microcytic anemia was seen in 7/7 patients. Colonoscopy showed abnormal findings in 7/9 (77.7%). Surgery was indicated for 6/9 patients due to acute aortic regurgitation and left ventricular failure. All patients were discharged home.

Conclusions: S. bovis most frequently affected the aortic valve of male patients. Colon disease was frequent. Surgery was indicated frequently due to hemodynamic compromise.

Keywords: Cardiac surgery; Colonic lesions; Infective endocarditis; Streptococcus bovis group.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Colonic Diseases / complications*
  • Colonic Diseases / microbiology
  • Colonoscopy
  • Endocarditis, Bacterial / complications*
  • Endocarditis, Bacterial / microbiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prospective Studies
  • Streptococcal Infections / complications*
  • Streptococcal Infections / microbiology
  • Streptococcus bovis / isolation & purification*