1 aDepartment of Exercise Science, Shippensburg University of Pennsylvania, Pennsylvania, USA bKidney Research Centre, Chronic Disease Program, Ottawa Hospital Research Institute, Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario, Canada cDepartment of Pharmacology and Cardiovascular Center, Center for Neurosciences C4N, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium dDepartment of Cardiovascular Sciences, University of Leicester, Cardiovascular Research Centre, Glenfield General Hospital, Leicester, United Kingdom eFaculty of Medicine, Division of Experimental Medicine, McGill University, Montreal, Canada fDepartment of Internal Medicine, Yale New Haven Hospital, Yale School of Medicine, Connecticut, USA gHypertension in Africa Research Team (HART), North-West University (Potchefstroom campus), South Africa hFaculty of Science and Technology, School of Applied and Biomedical Sciences, Federation University Australia, VIC, Australia iHypertension and Vascular Research Unit, Lady Davis Institute for Medical Research, Sir Mortimer B. Davis-Jewish General Hospital, McGill University, Montreal, Quebec, Canada jInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom kHypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan, USA lUniversidad de los Andes, Medical School, Bogota, Colombia mDepartment of Exercise Science, Shippensburg University of Pennsylvania, Boston University School of Medicine, Boston, Massachusetts, USA.