New flavonoid glycosides and other chemical constituents from Clerodendrum phlomidis leaves: isolation and characterisation

Yogesh P Bharitkar; Abhijit Hazra; Siddharth Shah; Sudeshna Saha; Anil Kumar Matoori; Nirup B Mondal

doi:10.1080/14786419.2015.1009457

New flavonoid glycosides and other chemical constituents from Clerodendrum phlomidis leaves: isolation and characterisation

Nat Prod Res. 2015;29(19):1850-6. doi: 10.1080/14786419.2015.1009457. Epub 2015 Feb 12.

Authors

Yogesh P Bharitkar¹, Abhijit Hazra, Siddharth Shah, Sudeshna Saha, Anil Kumar Matoori, Nirup B Mondal

Affiliation

¹ a Department of Chemistry , Indian Institute of Chemical Biology, Council of Scientific and Industrial Research , 4 Raja S. C. Mullick Road, Jadavpur , Kolkata 700 032 , India.

PMID: 25674969
DOI: 10.1080/14786419.2015.1009457

Abstract

Phytochemical investigation of the plant Clerodendrum phlomidis Linn. F. (Lamiaceae) has now led to the isolation of two new flavonoid glycosides (1, 2) together with six known compounds identified as pectolinaringenin (3), pectolinaringenin-7-O-β-D-glucopyranoside (4), 24β-ethylcholesta-5,22E,25-triene-3β-ol (5), 24β-ethylcholesta-5,22E,25-triene-3β-O-β-D-glucopyranoside (6), (2S,3S,4R,10E)-2-[(2'R)-2'-hydroxytetracosanoylamino]-10-octadecene-1,3,4-triol (7) and andrographolide (8) mainly by spectroscopic analysis. Compounds 4 and 6-8 are reported for the first time from C. phlomidis.

Keywords: 2D NMR (HSQC; COSY; Clerodendrum phlomidis; HMBC; NOESY); flavonoid glycosides.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Clerodendrum / chemistry*
Flavonoids / chemistry*
Flavonoids / isolation & purification
Glycosides / chemistry*
Glycosides / isolation & purification
Molecular Structure
Plant Leaves / chemistry
Plants, Medicinal / chemistry

Substances

Flavonoids
Glycosides