Hb S/β+-thalassemia due to Hb sickle and a novel deletion of DNase I hypersensitive sites HS3 and HS4 of the β locus control region

Haematologica. 2015 May;100(5):e166-8. doi: 10.3324/haematol.2014.117408. Epub 2015 Feb 14.

Authors

Affiliations

¹ Division of Hematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.
² Hamilton Regional Laboratory Medicine Program, Hamilton Health Sciences, Hamilton, Ontario, Canada.
³ Hamilton Regional Laboratory Medicine Program, Hamilton Health Sciences, Hamilton, Ontario, Canada Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada waye@hhsc.ca.

No abstract available

Keywords: DNase I hypersensitive sites; Hb S/β+-thalassemia; locus control region; novel deletion.

Publication types

Case Reports
Letter

MeSH terms

Anemia, Sickle Cell / diagnosis
Anemia, Sickle Cell / genetics*
Base Sequence
Child
Chromosome Mapping
Genetic Association Studies
Hemoglobin, Sickle / genetics*
Heterozygote
Humans
Locus Control Region*
Male
Molecular Sequence Data
Multigene Family
Mutation
Phenotype
Sequence Deletion*
beta-Globins / genetics*
beta-Thalassemia / diagnosis
beta-Thalassemia / genetics*

Substances

Hemoglobin, Sickle
beta-Globins