The effects of maternal weight and age on pre-eclampsia and eclampsia in Haiti

J Matern Fetal Neonatal Med. 2016;29(4):602-6. doi: 10.3109/14767058.2015.1012064. Epub 2015 Feb 24.

Abstract

Objective: Patient data from Maison de Naissance (MN), a rural maternity clinic in Haiti, were analyzed to determine the prevalence of pregnancy-related hypertensive disorders and the extent to which maternal weight and age are associated with these disorders in the MN population.

Methods: A case-control study design was used with cases defined as pregnant women who were presented at MN with pregnancy-related hypertensive disorders (pregnancy-induced hypertension, pre-eclampsia or eclampsia) and controls defined as those women who delivered babies at MN and were not diagnosed with a pregnancy-related hypertensive disorder. The final cohort size was 622 controls and 67 cases. Odds ratios were calculated using multivariate logistic regression.

Results: The incidence of pre-eclampsia and eclampsia was 7.0%. Older maternal age at delivery (OR = 3.18; 95%CI: 1.31, 7.76) and higher maternal weight (OR = 3.24; 95%CI: 1.76, 5.98) measured during prenatal care were significantly associated with pregnancy-related hypertensive disorders. Prenatal care was not significantly associated with reduced risk of pre-eclampsia/eclampsia.

Conclusions: The prevalence of pregnancy-related hypertensive disorders was high relative to rates in other developing countries. More is required to reduce the rate of pre-eclampsia perhaps by targeting older and women with high weight for preconception and more intensive prenatal care.

Keywords: Maternal health; pregnancy induced hypertension; prenatal care.

MeSH terms

  • Adolescent
  • Adult
  • Body Weight*
  • Case-Control Studies
  • Eclampsia / epidemiology*
  • Female
  • Haiti / epidemiology
  • Humans
  • Hypertension, Pregnancy-Induced / epidemiology
  • Maternal Age*
  • Middle Aged
  • Multivariate Analysis
  • Pre-Eclampsia / epidemiology*
  • Pregnancy
  • Young Adult