Computed tomography imaging of coronary artery plaque: characterization and prognosis

Abstract

The exact definition and prognostication of vulnerable plaque remain elusive, and multiple imaging modalities aim to identify these plaques. As a noninvasive technique for the diagnosis of coronary artery disease, coronary computed tomography angiography has become increasingly utilized, primarily in patients with an elevated cardiovascular risk profile. Recent advances in technical methods have allowed for improved visualization of the vessel wall and surrounding tissue, allowing for improved characterization of vulnerable plaques by identifying features such as low-density plaques, positive remodeling, and spotty calcification. Quantification and qualification of these plaques may enhance the ability to predict future cardiovascular events.

Keywords: Characterization; Coronary artery disease; Coronary computed tomography; Coronary plaque; Prognosis.