Lack of correlation between radiosensitivity and inhibition of DNA synthesis in hybrids (A-T x HeLa)

K Komatsu; Y Okumura; S Kodama; M Yoshida; R C Miller

doi:10.1080/09553008914552331

Lack of correlation between radiosensitivity and inhibition of DNA synthesis in hybrids (A-T x HeLa)

Int J Radiat Biol. 1989 Dec;56(6):863-7. doi: 10.1080/09553008914552331.

Authors

K Komatsu¹, Y Okumura, S Kodama, M Yoshida, R C Miller

Affiliation

¹ Atomic Disease Institute, Nagasaki University School of Medicine, Japan.

PMID: 2574215
DOI: 10.1080/09553008914552331

Abstract

Hybrid cells obtained from A-T and D98/AH(HeLa) cells showed normal radiation sensitivity to cell killing, but retained radioresistant DNA synthesis similar to parental A-T cells.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Ataxia Telangiectasia / genetics
Cell Survival / radiation effects
DNA / biosynthesis*
Dose-Response Relationship, Radiation
HeLa Cells
Humans
Hybrid Cells / radiation effects*
In Vitro Techniques
Phenotype
Radiation Tolerance*

Substances

DNA