Two cases of acute severe flaccid myelitis associated with enterovirus D68 infection in children, Norway, autumn 2014

H C Pfeiffer; K Bragstad; M K Skram; H Dahl; P K Knudsen; M S Chawla; M Holberg-Petersen; K Vainio; S G Dudman; A M Kran; A E Rojahn

doi:10.2807/1560-7917.es2015.20.10.21062

Two cases of acute severe flaccid myelitis associated with enterovirus D68 infection in children, Norway, autumn 2014

Euro Surveill. 2015 Mar 12;20(10):21062. doi: 10.2807/1560-7917.es2015.20.10.21062.

Authors

H C Pfeiffer¹, K Bragstad, M K Skram, H Dahl, P K Knudsen, M S Chawla, M Holberg-Petersen, K Vainio, S G Dudman, A M Kran, A E Rojahn

Affiliation

¹ Department of Paediatrics, Oslo University Hospital, Oslo, Norway.

PMID: 25788251
DOI: 10.2807/1560-7917.es2015.20.10.21062

Abstract

Enterovirus D68 (EV-D68), phylogenetic clade B was identified in nasopharyngeal specimens of two cases of severe acute flaccid myelitis. The cases were six and five years-old and occurred in September and November 2014. EV-D68 is increasingly associated with acute flaccid myelitis in children, most cases being reported in the United States. Awareness of this possible neurological complication of enterovirus D68 infection is needed.

MeSH terms

Child
Child, Preschool
Electroencephalography
Enterovirus D, Human / classification
Enterovirus D, Human / genetics*
Enterovirus D, Human / isolation & purification*
Enterovirus Infections / diagnosis*
Enterovirus Infections / virology
Female
Humans
Magnetic Resonance Imaging
Myelitis / diagnosis*
Myelitis / virology
Nasopharynx / virology*
Norway
Paralysis / diagnosis*
Paralysis / virology
Reverse Transcriptase Polymerase Chain Reaction
Seasons
Sequence Analysis, DNA
Severity of Illness Index