Lethal 5-fluorouracil toxicity in a colorectal patient with severe dihydropyrimidine dehydrogenase (DPD) deficiency

Int J Colorectal Dis. 2016 Mar;31(3):699-701. doi: 10.1007/s00384-015-2191-0. Epub 2015 Mar 22.

Carole Dhelens^{1

2}, Agnès Bonadona³, Fabienne Thomas^{4

5}, Claire Chapuis⁶, Leila Potton³, Sabrina Marsili^{4

5}, Pierrick Bedouch^{6

7}, Carole Schwebel^{3

8}

¹ Department of Pharmacy, Centre Hospitalier Universitaire de Grenoble, Grenoble, France. caroledhelens@yahoo.fr.
² CHU Grenoble, Pôle Pharmacie, Pharmacie clinique, Pavillon Vercors, CS 10217, 38043, Grenoble cedex 9, France. caroledhelens@yahoo.fr.
³ Department of Medical Intensive Care Unit, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.
⁴ Department of Pharmacology, IUCT-O, Institut Claudius Regaud, Toulouse, France.
⁵ University Toulouse III Paul Sabatier/EA4553, Toulouse, France.
⁶ Department of Pharmacy, Centre Hospitalier Universitaire de Grenoble, Grenoble, France.
⁷ Grenoble-Alpes University UJF-Grenoble 1/CNRS/TIMC-IMAG, UMR 5525/Themas, Grenoble, France.
⁸ Grenoble-Alpes University UJF Grenoble 1/Inserm U1039, Grenoble, France.

No abstract available

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