Performance of Alere Determine HIV-1/2 Ag/Ab Combo rapid test for acute HIV infection: a case report

Infez Med. 2015 Mar;23(1):48-50.

Abstract

We describe a case of symptomatic acute HIV infection in a young man where a fourth-generation rapid screening test combining HIV-specific antibody and p24 antigen was negative. In highly suspicious cases of acute HIV infection, plasma HIV RNA assays together with conventional, non-rapid screening tests should be used.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • HIV Antibodies / blood*
  • HIV Antigens / blood*
  • HIV Infections / diagnosis*
  • HIV Infections / immunology
  • HIV Infections / virology
  • HIV-1 / immunology
  • HIV-1 / isolation & purification*
  • HIV-2 / immunology
  • HIV-2 / isolation & purification*
  • Humans
  • Immunoassay / methods
  • Male
  • Predictive Value of Tests
  • Sensitivity and Specificity

Substances

  • HIV Antibodies
  • HIV Antigens