Gut microbiota: the link to your second brain

Vanessa Ridaura; Yasmine Belkaid

doi:10.1016/j.cell.2015.03.033

Gut microbiota: the link to your second brain

Cell. 2015 Apr 9;161(2):193-4. doi: 10.1016/j.cell.2015.03.033.

Authors

Vanessa Ridaura¹, Yasmine Belkaid²

Affiliations

¹ Program in Barrier Immunity and Repair, National Institute of Allergy and Infectious Disease, NIH, Bethesda, MD 20892, USA; Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Disease, NIH, Bethesda, MD 20892, USA.
² Program in Barrier Immunity and Repair, National Institute of Allergy and Infectious Disease, NIH, Bethesda, MD 20892, USA; Mucosal Immunology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Disease, NIH, Bethesda, MD 20892, USA. Electronic address: ybelkaid@niaid.nih.gov.

PMID: 25860600
DOI: 10.1016/j.cell.2015.03.033

Abstract

Serotonin is a highly ubiquitous signaling molecule that plays a role in the regulation of various physiological functions. Several lines of evidence, including the present work from Hsiao and colleagues, demonstrate that, in the gut, microbial-derived metabolites affect the production of serotonin that in turn impacts host physiological functions.

Publication types

Comment

MeSH terms

Animals
Bacteria / metabolism*
Gastrointestinal Tract / microbiology*
Humans
Microbiota*
Serotonin / biosynthesis*

Substances

Serotonin