Optimization of Vitamin D Status After Roux-en-Y Gastric Bypass Surgery in Obese Patients Living in Northern Climate

Obes Surg. 2015 Dec;25(12):2321-7. doi: 10.1007/s11695-015-1685-8.

Abstract

Background: Patients who undergo bariatric surgery are at risk for micronutrient deficiencies. The aims of this study were to determine the prevalence and predictors of vitamin D deficiency in obese patients residing in the northern climate, and to evaluate the effectiveness of a daily maintenance dose of vitamin D 2000 IU in preventing hypovitaminosis D within 1 year after bariatric surgery.

Methods: A cohort study involving adult patients undergoing RYGB was conducted. Longitudinal changes in serum vitamin D concentrations and clinical parameters were measured and collected.

Results: Data from 134 recipients of RYGB were analyzed. Hypovitaminosis D was identified in 86 patients (64 %), and was significantly affected by seasonal change and the number of comorbidities. Follow-up data were available in 60 patients. Vitamin D sufficiency was achieved in 62.5 % of those patients with baseline vitamin D insufficiency. A dose-response relationship of vitamin D intake was observed, with the most significant increase in 25(OH)D associated with daily vitamin D intakes ≥ 2000 IU.

Conclusions: The prevalence of hypovitaminosis D before RYGB was comparable to patients living in the non-northern climate. Daily vitamin D intake meeting at least 2000 IU is associated with greater improvement in serum vitamin D concentration.

Keywords: Bariatric surgery; Northern climate; Roux-en-Y gastric bypass; Vitamin D.

MeSH terms

  • Adult
  • Bariatric Surgery / adverse effects
  • Bariatric Surgery / statistics & numerical data
  • Climate*
  • Cold Temperature
  • Female
  • Gastric Bypass* / adverse effects
  • Gastric Bypass* / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Obesity, Morbid / blood*
  • Obesity, Morbid / epidemiology
  • Obesity, Morbid / surgery*
  • Prevalence
  • Retrospective Studies
  • Seasons
  • Vitamin D / blood*
  • Vitamin D Deficiency / blood
  • Vitamin D Deficiency / epidemiology
  • Young Adult

Substances

  • Vitamin D