Fatty acid and phospholipase A2 plasma levels in children with autism

Trends Psychiatry Psychother. 2013;35(1):76-80. doi: 10.1590/s2237-60892013000100009.

Abstract

Objective: To evaluate fatty acid plasma levels, phospholipase A2 activity, and the developmental profiles of children with autism vs. control subjects.

Methods: Twenty four children with autism underwent laboratory analysis for fatty acid quantification using gas chromatography and PLA2 activity determination by fluorometric assay.

Results: No correlation was observed between the developmental quotient and fatty acid plasma levels. Phospholipase A2 activity was significantly higher among autistic children compared with controls.

Conclusion: The study did not show a correlation between fatty acid and phospholipase A2 plasma levels and the developmental profile of children with autism.