Treatment of an adolescent with chronic myeloid leukemia and the T315I mutation with ponatinib

MeSH terms

• Adolescent
• Amino Acid Substitution
• Child
• Fusion Proteins, bcr-abl* / antagonists & inhibitors
• Fusion Proteins, bcr-abl* / genetics
• Humans
• Imidazoles / administration & dosage*
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / drug therapy
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / enzymology
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive* / genetics
• Male
• Mutation, Missense*
• Protein Kinase Inhibitors / administration & dosage*
• Pyridazines / administration & dosage*