VWF propeptide in defining VWD subtypes

Blood. 2015 May 7;125(19):2882-3. doi: 10.1182/blood-2015-03-629832.

Abstract

In this issue of Blood, Sanders and coworkers define the pathophysiology of types 1, 2, and 3 von Willebrand disease (VWD) in the Willebrand in the Netherlands (WiN) study by using the ratios of von Willebrand factor propeptide (VWFpp) or factor VIII activity to VWF antigen.

Publication types

  • Comment

MeSH terms

  • Female
  • Hemorrhage / pathology*
  • Humans
  • Male
  • Mutation / genetics*
  • Protein Precursors / genetics*
  • von Willebrand Diseases / classification*
  • von Willebrand Diseases / genetics*
  • von Willebrand Factor / genetics*

Substances

  • Protein Precursors
  • von Willebrand Factor