Under treatment of pneumonia among children under 5 years of age in a malaria-endemic area: population-based surveillance study conducted in Manhica district- rural, Mozambique

Int J Infect Dis. 2015 Jul:36:39-45. doi: 10.1016/j.ijid.2015.05.010. Epub 2015 May 14.

Abstract

Background: Integrated Management of Childhood Illness (IMCI) guidelines were developed to decrease morbidity and mortality, yet implementation varies across settings. Factors associated with poor adherence are not well understood.

Methods: We used data from Manhiça District Hospital outpatient department and five peripheral health centers to examine pneumonia management for children <5 years old from January 2008 to June 2011. Episodes of IMCI-defined pneumonia (cough or difficult breathing plus tachypnea), severe pneumonia (pneumonia plus chest wall in-drawing), and/or clinician-diagnosed pneumonia (based on discharge diagnosis) were included.

Results: Among severe pneumonia episodes, 96.2% (2,918/3,032) attended in the outpatient department and 70.0% (291/416) attended in health centers were appropriately referred to the emergency department. Age<1 year, malnutrition and various physical exam findings were associated with referral. For non-severe pneumonia episodes, antibiotics were prescribed in 45.7% (16,094/35,224). Factors associated with antibiotic prescription included age <1 year, abnormal auscultatory findings, and clinical diagnosis of pneumonia; diagnosis of malaria or gastroenteritis and pallor were negatively associated with antibiotic prescription.

Conclusion: Adherence to recommended management of severe pneumonia was high in a hospital outpatient department, but suboptimal in health centers. Antibiotics were prescribed in fewer than half of non-severe pneumonia episodes, and diagnosis of malaria was the strongest risk factor for incorrect management.

Keywords: Guideline Adherence; Mozambique; Pneumonia.

MeSH terms

  • Ambulatory Care
  • Child, Preschool
  • Coinfection / diagnosis
  • Drug Prescriptions
  • Female
  • Guideline Adherence
  • Humans
  • Infant
  • Malaria / complications*
  • Malaria / epidemiology
  • Male
  • Mozambique / epidemiology
  • Pneumonia / complications
  • Pneumonia / diagnosis
  • Pneumonia / drug therapy
  • Pneumonia / therapy*
  • Population Surveillance
  • Referral and Consultation
  • Risk Factors
  • Rural Population