A generalized slab-wise framework for parallel transmit multiband RF pulse design

Magn Reson Med. 2016 Apr;75(4):1444-56. doi: 10.1002/mrm.25689. Epub 2015 May 20.

Abstract

Purpose: We propose a new slab-wise framework to design parallel transmit multiband pulses for volumetric simultaneous multislice imaging with a large field of view along the slice direction (FOVs).

Theory and methods: The slab-wise framework divides FOVs into a few contiguous slabs and optimizes pulses for each slab. Effects of relevant design parameters including slab number and transmit B1 (B1+) mapping slice placement were investigated for human brain imaging by designing pulses with global or local SAR control based on electromagnetic simulations of a 7T head RF array. Pulse design using in vivo B1+ maps was demonstrated and evaluated with Bloch simulations.

Results: RF performance with respect to SAR reduction or B1+ homogenization across the entire human brain improved with increasing slabs; however, this improvement was nonlinear and leveled off at ∼12 slabs when the slab thickness reduced to ∼12 mm. The impact of using different slice placements for B1+ mapping was small.

Conclusion: Compared with slice-wise approaches where each of the many imaging slices requires both B1+ mapping and pulse optimization, the proposed slab-wise design framework attained comparable RF performance while drastically reducing the number of required pulses; therefore, it can be used to increase time efficiency for B1+ mapping, pulse calculation, and sequence preparation.

Keywords: high-field MRI; multiband RF pulse design; parallel excitation; simultaneous multislice imaging; transmit B1 homogenization.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms
  • Brain / diagnostic imaging
  • Humans
  • Imaging, Three-Dimensional / methods*
  • Magnetic Resonance Imaging / methods*
  • Neuroimaging / methods*