Objective: This study aimed at determining the prevalence of psychosis in tuberculosis (TB) patients in comparison to nontuberculosis control and its correlation with disease pattern.
Method: One hundred and fifteen patients with TB and 112 family members visiting the multidrug treatment-resistant treatment center at University College Hospital Ibadan Centre were screened for psychological distress with the General Health Questionnaire (GHQ-12). Presence of a psychotic condition was determined by the Psychosis Screening Questionnaire and the Structured Clinical Interview for DSM-IV Axis I Disorder and was compared with severity of pulmonary TB.
Results: After adjusting for age, predictors of high/positive GHQ include the following: duration of TB ≥4years [odds ratio (OR)=4.02, 95% confidence interval (CI)=1.29-11.13], extrapulmonary TB (OR=3.45, 95% CI=1.02-14.11), severe disease extent (OR=5.27, 95% CI=1.05-13.01) and disease category 2 (OR=2.38, 95% CI=1.01-7.99), and predictors of psychosis are as follows: duration of TB ≥4years (OR=3.99, 95% CI=1.51-9.88), extrapulmonary TB (OR=3.88, 95% CI=1.55-9.98), severe disease extent (OR=9.55, 95% CI=2.15-18.05) and disease category 2 (OR=2.86, 95% CI=1.14-7.55).
Conclusion: In view of high prevalence of psychological distress and psychosis in TB, care of TB patients should include consultative-liaison psychiatric care.
Keywords: Consultative–liaison psychiatry; Psychological distress; Psychosis; Tuberculosis.
Copyright © 2015. Published by Elsevier Inc.