Assessing the histological type and grade of primary parotid carcinoma by fine-needle aspiration and frozen section

Shuji Nishikawa; Ryo Kawata; Masaaki Higashino; Koutetsu Lee; Tetsuya Terada; Yoshitaka Kurisu; Motomu Tsuji

doi:10.1016/j.anl.2015.03.002

Assessing the histological type and grade of primary parotid carcinoma by fine-needle aspiration and frozen section

Auris Nasus Larynx. 2015 Dec;42(6):463-8. doi: 10.1016/j.anl.2015.03.002. Epub 2015 Jun 9.

Authors

Shuji Nishikawa¹, Ryo Kawata², Masaaki Higashino², Koutetsu Lee², Tetsuya Terada², Yoshitaka Kurisu³, Motomu Tsuji³

Affiliations

¹ Department of Otolaryngology and Head and Neck Surgery, Osaka Medical College, Takatsuki, Japan. Electronic address: oto055@poh.osaka-med.ac.jp.
² Department of Otolaryngology and Head and Neck Surgery, Osaka Medical College, Takatsuki, Japan.
³ Division of Surgical Pathology, Osaka Medical College, Takatsuki, Japan.

PMID: 26065980
DOI: 10.1016/j.anl.2015.03.002

Abstract

Objective: The aim of this study is to compare preoperative fine needle aspiration cytology (FNAC) and intraoperative frozen section (FS) for the correct identification of malignancy, histological grade, and histological type.

Methods: FNAC was performed on all 105 patients and FS on 71 patients with parotid carcinoma.

Results: The rate of correctly determining the histological grade by FNAC and FS was 32% and 73%, respectively. The correct diagnosis rate for both the histological type and grade by FNAC and FS was 20% and 48%, respectively.

Conclusions: The correct grading of both high and low/intermediate grade carcinoma is possible in 70-80% of patients by FS. If the histological grade is identified correctly, the extent of resection can usually be decided appropriately. Therefore, we should put emphasis on determining the histological grade.

Keywords: Fine-needle aspiration cytology; Frozen section; Histological grade; Histological type; Parotid carcinoma.

MeSH terms

Adenocarcinoma / diagnosis
Adenocarcinoma / pathology*
Biopsy, Fine-Needle
Carcinoma, Acinar Cell / diagnosis
Carcinoma, Acinar Cell / pathology
Carcinoma, Adenoid Cystic / diagnosis
Carcinoma, Adenoid Cystic / pathology
Carcinoma, Ductal / diagnosis
Carcinoma, Ductal / pathology
Carcinoma, Mucoepidermoid / diagnosis
Carcinoma, Mucoepidermoid / pathology
Carcinoma, Squamous Cell / diagnosis
Carcinoma, Squamous Cell / pathology*
Cohort Studies
Cystadenocarcinoma / diagnosis
Cystadenocarcinoma / pathology
Frozen Sections
Head and Neck Neoplasms / diagnosis
Head and Neck Neoplasms / pathology*
Humans
Myoepithelioma / diagnosis
Myoepithelioma / pathology
Neoplasm Grading
Neoplasm Staging
Parotid Neoplasms / diagnosis
Parotid Neoplasms / pathology*
Retrospective Studies
Squamous Cell Carcinoma of Head and Neck