Exploration of the Visual System: Part 2: In Vivo Analysis Methods: Virtual-Reality Optomotor System, Fundus Examination, and Fluorescent Angiography

Fabienne Marcelli; Pascal Escher; Daniel F Schorderet

doi:10.1002/9780470942390.mo110177

Exploration of the Visual System: Part 2: In Vivo Analysis Methods: Virtual-Reality Optomotor System, Fundus Examination, and Fluorescent Angiography

Curr Protoc Mouse Biol. 2012 Sep 1;2(3):207-18. doi: 10.1002/9780470942390.mo110177.

Authors

Fabienne Marcelli^{1

2}, Pascal Escher^{1

3}, Daniel F Schorderet^{1

3

2}

Affiliations

¹ IRO (Institute for Research in Ophthalmology), Sion, Switzerland.
² EPFL (Ecole Polytechnique Fédérale), Lausanne, Switzerland.
³ Department of Ophthalmology, University of Lausanne, Lausanne, Switzerland.

PMID: 26069012
DOI: 10.1002/9780470942390.mo110177

Abstract

The mouse has emerged as an animal model for many diseases. At IRO, we have used this animal to understand the development of many eye diseases and treatment of some of them. Precise evaluation of vision is a prerequisite for both these approaches. In this unit we describe three ways to measure vision: testing the optokinetic response, and evaluating the fundus by direct observation and by fluorescent angiography. Curr. Protoc. Mouse Biol. 2:207-218 © 2012 by John Wiley & Sons, Inc.

Keywords: contrast sensitivity; fluorescent angiography; fundus; ophthalmology; optokinetic response; spatial frequency.