Transplantation of Macaca cynomolgus iPS-derived hematopoietic cells in NSG immunodeficient mice

Soumeya Abed; Alisa Tubsuwan; Porntip Chaichompoo; In Hyun Park; Alice Pailleret; Aïssa Benyoucef; Lucie Tosca; Edouard De Dreuzy; Anais Paulard; Marine Granger-Locatelli; Francis Relouzat; Stéphane Prost; Gerard Tachdjian; Suthat Fucharoen; George Q Daley; Emmanuel Payen; Stany Chrétien; Philippe Leboulch; Leïla Maouche-Chrétien

doi:10.3324/haematol.2015.127373

Transplantation of Macaca cynomolgus iPS-derived hematopoietic cells in NSG immunodeficient mice

Haematologica. 2015 Oct;100(10):e428-31. doi: 10.3324/haematol.2015.127373. Epub 2015 Jun 18.

Authors

Soumeya Abed¹, Alisa Tubsuwan², Porntip Chaichompoo², In Hyun Park³, Alice Pailleret⁴, Aïssa Benyoucef⁵, Lucie Tosca⁶, Edouard De Dreuzy¹, Anais Paulard⁷, Marine Granger-Locatelli⁴, Francis Relouzat⁴, Stéphane Prost⁴, Gerard Tachdjian⁶, Suthat Fucharoen⁸, George Q Daley³, Emmanuel Payen⁹, Stany Chrétien⁹, Philippe Leboulch¹⁰, Leïla Maouche-Chrétien¹¹

Affiliations

¹ CEA, Institute of Emerging Diseases and Innovative Therapies (iMETI), Université Paris Sud 11, France Inserm, Paris, France Université Paris 7, France.
² CEA, Institute of Emerging Diseases and Innovative Therapies (iMETI), Université Paris Sud 11, France Inserm, Paris, France Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Department of Biochemistry, Faculty of Medicine Siriraj Hospital and Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
³ Division of Pediatric Hematology/Oncology, Children's Hospital Boston, and Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA, USA.
⁴ CEA, Institute of Emerging Diseases and Innovative Therapies (iMETI), Université Paris Sud 11, France.
⁵ CEA, Institute of Emerging Diseases and Innovative Therapies (iMETI), Université Paris Sud 11, France Inserm U967 - CEA / DSV / IRCM, Fontenay Aux Roses Cedex, France.
⁶ Hôpital Antoine Béclère, Service d'Histologie Embryologie Cytogénétique, "Assistance Publique - Hôpitaux de Paris", Clamart, France.
⁷ Bluebirdbio, Cambridge, MA, USA.
⁸ Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Department of Biochemistry, Faculty of Medicine Siriraj Hospital and Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
⁹ CEA, Institute of Emerging Diseases and Innovative Therapies (iMETI), Université Paris Sud 11, France Inserm, Paris, France.
¹⁰ CEA, Institute of Emerging Diseases and Innovative Therapies (iMETI), Université Paris Sud 11, France Genetics Division, Department of Medicine, Brigham & Women's Hospital and Harvard Medical School, Boston, MA, USA.
¹¹ CEA, Institute of Emerging Diseases and Innovative Therapies (iMETI), Université Paris Sud 11, France Inserm, Paris, France leila.maouche@inserm.fr.

No abstract available

Keywords: Engraftment of cy-iPSC-derived hematopoietic cells; Induced pluripotent stem cells; Nonhuman primate.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Hematopoietic Stem Cell Transplantation*
Hematopoietic Stem Cells / cytology*
Hematopoietic Stem Cells / metabolism
Immunocompromised Host
Induced Pluripotent Stem Cells / cytology*
Macaca
Mice
Models, Animal