Emergence of a new GII.17 norovirus variant in patients with acute gastroenteritis in Jiangsu, China, September 2014 to March 2015

Euro Surveill. 2015 Jun 18;20(24):21157. doi: 10.2807/1560-7917.es2015.20.24.21157.

Abstract

From September 2014 to March 2015, 23 outbreaks of norovirus (NoV) acute gastroenteritis occurred in Jiangsu, China. Partial sequencing of the NoV capsid gene suggested that 16 of the 23 outbreaks were related to a new GII.17 variant. This variant was first detected in sporadic specimens in October 2014, and became predominant in February 2015. Analysis of the RNA-dependent RNA polymerase (RdRp), and complete capsid including the protruding domain P2 sequences confirmed this GII.17 variant as distinct from previously identified GII variants.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Caliciviridae Infections / diagnosis
  • Caliciviridae Infections / epidemiology
  • Caliciviridae Infections / virology*
  • China / epidemiology
  • Disease Outbreaks*
  • Gastroenteritis / diagnosis
  • Gastroenteritis / epidemiology
  • Gastroenteritis / virology*
  • Genetic Variation*
  • Genotype
  • Humans
  • Male
  • Molecular Sequence Data
  • Norovirus / classification
  • Norovirus / genetics*
  • Norovirus / isolation & purification*
  • Phylogeny
  • Population Surveillance
  • Prevalence
  • RNA, Viral / genetics
  • Sequence Analysis, DNA
  • Young Adult

Substances

  • RNA, Viral