Mitigating Fear and Loathing in Managing Acute Myeloid Leukemia

Semin Hematol. 2015 Jul;52(3):249-55. doi: 10.1053/j.seminhematol.2015.03.009. Epub 2015 Mar 17.

Abstract

The contemporary care of patients with acute myeloid leukemia (AML) is made complex by potentially toxic treatments, continuously advancing science, aging patients, and individual treatment goals. By taking a survey of present-day approaches, we aim to dispel some of the trepidation surrounding that care of patients with AML. At the beginning is the initial presentation, and we will discuss whether or not AML should be considered a medical emergency. We will explore the complex realm of patient decision-making about initial therapy, including the intricate straits of patient-doctor communication, and available options for initial treatment. We will then address post-remission approaches and the controversies that lie therein, and survivorship issues. Finally, we will investigate the current role molecular assessments are playing in therapy recommendations.

Publication types

  • Review

MeSH terms

  • Biomarkers, Tumor / analysis
  • Decision Making
  • Fear*
  • Humans
  • Leukemia, Myeloid, Acute / genetics
  • Leukemia, Myeloid, Acute / psychology*
  • Leukemia, Myeloid, Acute / therapy
  • Mutation
  • Physician-Patient Relations

Substances

  • Biomarkers, Tumor