Literature review of rheumatoid arthritis in India

Int J Rheum Dis. 2016 May;19(5):440-51. doi: 10.1111/1756-185X.12621. Epub 2015 Jul 14.

Abstract

Aim: Rheumatoid arthritis (RA) can lead to severe disability. This literature review assessed the descriptive epidemiology, comorbidities and extra-articular manifestations, functioning abilities and quality of life, and treatment patterns of RA patients in India.

Method: A literature review of all observational studies published from 1985 to 2012 was conducted using MEDLINE and Embase. Quantitative and qualitative findings were summarized.

Results: Twenty-eight studies were identified for data extraction. Seven described the descriptive epidemiology of RA, 14 described comorbidities and extra-articular manifestations, nine described the functioning abilities and quality of life among patients, and 10 provided information on treatments.

Conclusion: This review is confined to studies with small sample sizes, cross-sectional designs, and/or clinical settings that may not be representative of the entire Indian population. There is a need for more robust studies, as conclusions for the entire Indian RA population cannot be drawn from only the current observational studies.

Keywords: India; literature review; rheumatoid arthritis.

Publication types

  • Review

MeSH terms

  • Antirheumatic Agents / adverse effects
  • Antirheumatic Agents / therapeutic use*
  • Arthritis, Rheumatoid / diagnosis
  • Arthritis, Rheumatoid / drug therapy*
  • Arthritis, Rheumatoid / epidemiology
  • Comorbidity
  • Disability Evaluation
  • Humans
  • India / epidemiology
  • Observational Studies as Topic
  • Risk Factors
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Antirheumatic Agents